8-Cyclopentyl-1,3-dipropylxanthine (DPCPX, PD-116,948) is a drug which acts as a potent and selective antagonist for the adenosine A1 receptor. It has high selectivity for A1 over other adenosine receptor subtypes, but as with other xanthine derivatives DPCPX also acts as a phosphodiesterase inhibitor, and is almost as potent as rolipram at inhibiting PDE4. It has been used to study the function of the adenosine A1 receptor in animals, which has been found to be involved in several important functions such as regulation of breathing and activity in various regions of the brain, and DPCPX has also been shown to produce behavioural effects such as increasing the hallucinogen-appropriate responding produced by the 5-HT2A agonist DOI, and the dopamine release induced by MDMA, as well as having interactions with a range of anticonvulsant drugs.

CAS：102146-07-6
中文别名：1,3-二丙基-8-环戊基黄嘌呤;8-环戊-1,3-二丙基黄嘌呤;
英文别名：8-cyclopentyl-1,3-dipropyl-7H-purine-2,6-dione;8-Cyclopentyl-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione;
分子式：C16H24N4O2
分子量：304.387
精确质量：304.19
Psa：72.68
Logp：2.3639

MDL号：MFCD00055117
PubChem号：24277697

密度：1.195g/cm3
沸点：535.1ºC at 760mmHg
熔点：178°C
闪点：277.4ºC
折射率：1.564
蒸汽压：1.59E-11mmHg at 25°C

安全说明：S26-S36
WGK Germany：3
危险类别码：R36/37/38
海关编码：2933990090
危险品标志：Xi
信号词：Warning
危险标志：GHS07
危险性描述：H315; H319; H335
危险性防范说明：P261; P305 + P351 + P338