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化合物简介
2-Bromofluorobenzoic Acid is used in the preparation of boron-containing anti-fungal agents, in the treatment of onychomycosis. Also used in the synthesis of MEK 1,2-inhibitors possessing bidentate Ser212 interactions.
基本信息
CAS:1006-41-3
中文别名:
英文别名:4-Fluor-2-brom-benzoesaeure;2-Bromo-4-Fluorobenzoic Acid;2-Bromofluorobenzoic Acid;2-Brom-4-fluor-benzoesaeure;4-fluoro-2-bromo-benzoic acid;2-bromo-4-fluorobenzioc acid;2-bromo-4-fluoro-benzoic acid;2-Bromo-4-Fluorobenzoic;RARECHEM AL BO 1996;
分子式:C7H4BrFO2
分子量:219.008
精确质量:217.938
Psa:37.3
Logp:2.2864
中文别名:
英文别名:4-Fluor-2-brom-benzoesaeure;2-Bromo-4-Fluorobenzoic Acid;2-Bromofluorobenzoic Acid;2-Brom-4-fluor-benzoesaeure;4-fluoro-2-bromo-benzoic acid;2-bromo-4-fluorobenzioc acid;2-bromo-4-fluoro-benzoic acid;2-Bromo-4-Fluorobenzoic;RARECHEM AL BO 1996;
分子式:C7H4BrFO2
分子量:219.008
精确质量:217.938
Psa:37.3
Logp:2.2864
编号系统
MDL号:MFCD00055370
EINECS号:000-000-0
BRN号:2614292
EINECS号:000-000-0
BRN号:2614292
物化性质
外观与性状:白色固体
密度:1.535g/cm3
沸点:265.3ºC at 760mmHg
熔点:172-176°C(lit.)
闪点:114.3ºC
稳定性:Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
蒸汽压:0.000745mmHg at 25°C
密度:1.535g/cm3
沸点:265.3ºC at 760mmHg
熔点:172-176°C(lit.)
闪点:114.3ºC
稳定性:Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
蒸汽压:0.000745mmHg at 25°C
安全信息
安全说明:S26-S36-S37/39
WGK Germany:3
危险类别码:R36/37/38
海关编码:2916399090
危险品标志:Xi
WGK Germany:3
危险类别码:R36/37/38
海关编码:2916399090
危险品标志:Xi
生产方法及用途
用途
医药中间体。
医药中间体。
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
