Solketal is a protected form of glycerol with an isopropylidene acetal group joining two neighboring hydroxyl groups. Solketal contains a chiral center on the center carbon of the glycerol backbone, and so can be purchased as either the racemate or as one of the two enantiomers. Solketal has been used extensively in the synthesis of mono-, di- and triglycerides by ester bond formation. The free hydroxyl groups of solketal can be esterified with a carboxylic acid to form the protected monoglyceride, where the isopropylene group can then be removed using an acid catalyst in aqueous or alcoholic medium. The unprotected diol can then be esterified further to form either the di- or triglyceride.

CAS：100-79-8
中文别名：(+,-)-2,2-二甲基-4-羟基-1,3-二恶烷;
英文别名：Solketal;(±)-2,2-Dimethyl-1,3-dioxolane-4-methanol;1,2-Isopropylidene-rac-glycerol;(±)-2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane;2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane;1,2-Isopropylideneglycerol;1,2-O-Isopropylideneglycerol;1,3-Dioxolane-4-methanol, 2,2-dimethyl-;2,2-Dimethyl-1,3-dioxolane-4-methanol;
分子式：C6H12O3
分子量：132.158
精确质量：132.079
Psa：38.69
Logp：0.1302

BRN号：104465
MDL号：MFCD00063238
EINECS号：202-888-7
RTECS号：JI0400000

外观与性状：透明无色液体
密度：1.063
沸点：188-189ºC
闪点：80ºC
折射率：1.433-1.435
稳定性：Stable under normal temperatures and pressures.
储存条件：2-8ºC
蒸汽压：0.164mmHg at 25°C

RTECS号：JI0400000
安全说明：S24/25
WGK Germany：2
危险类别码：R36/37/38
海关编码：29329970
危险品标志：Xi

用途
可作为鲨肝醇的中间体，也可用作万能溶剂、增塑剂、药用辅料(助溶剂、悬浮剂)。