VANDERBILT UNIVERSITY; CONN, P., Jeffrey; LINDSLEY, Craig, W.; STAUFFER, Shaun, R.; JONES, Carrie, K.; CONDE-CEIDE, Susana; TONG, Han Min; BARTOLOME-NEBREDA, Jose, Manuel; MACDONALD, Gregor, James Patent: WO2012/78817 A1, 2012 ; WO 2012/078817 A1