GENENTECH, INC.; GIBBONS, Paul; HANAN, Emily; LIU, Wendy; LYSSIKATOS, Joseph P.; MAGNUSON, Steven R.; MENDONCA, Rohan; PASTOR, Richard; RAWSON, Thomas E.; SIU, Michael; ZAK, Mark E.; ZHOU, Aihe; ZHU, Bing-Yan Patent: WO2011/3065 A2, 2011 ; Location in patent: Page/Page column 110 ; WO 2011/003065 A2