METABOLEX, INC.; MA, Jingyuan; NOVACK, Aaron; NASHASHIBI, Imad; PHAM, Phuongly; RABBAT, Christopher J.; SONG, Jiangao; SHI, Dong Fang; ZHAO, Zuchun; CHOI, Yun-Jung; CHEN, Xin Patent: WO2010/48207 A2, 2010 ; Location in patent: Page/Page column 80 ; WO 2010/048207 A2