AMGEN INC.; BROWN, Matthew; CHEN, Yi; CUSHING, Timothy D.; GONZALEZ LOPEZ DE TURISO, Felix; HE, Xiao; KOHN, Todd J.; LOHMAN, Julia Winslow; PATTAROPONG, Vatee; SEGANISH, Jennifer; SHIN, Youngsook; SIMARD, Jillian L. Patent: WO2010/151737 A2, 2010 ; Location in patent: Page/Page column 144-145 ; WO 2010/151737 A2