SHIONOGI andamp;; CO., LTD.; MIKAMIYAMA, Hidenori; MATSUMURA, Akira; MASUI, Moriyasu; ANAN, Kosuke; HATA, Kayoko Patent: WO2010/114181 A1, 2010 ; Location in patent: Page/Page column 93 ; WO 2010/114181 A1