参考文献

VERTEX PHARMACEUTICALS INCORPORATED; LAUFFER, David; LI, Pan; MCGINTY, Kira; RONKIN, Steven; TANG, Qing; GRILLOT, Anne-Laure; WAAL, Nathan Patent: WO2010/48131 A1, 2010 ; Location in patent: Page/Page column 53 ; WO 2010/048131 A1