NOVARTIS AG; CALIENNI, John Vincent; DE LA CRUZ, Marilyn; FLUBACHER, Dietmar; GONG, Baoqing; KAPA, Prasad Koteswara; KARPINSKI, Piotr H.; LIU, Hui; MICHEL, Pascal; MOSE, Rasmus; TESTA, Maria Caterina; WAYKOLE, Liladhar Murlidhar Patent: WO2012/44727 A2, 2012 ; Location in patent: Page/Page column 62-63 ;