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  • 戊酸雌二醇

    Estradiol 17-Valerate

化合物简介

Estradiol valerate (EV, E2V) (INN, USAN, JAN) (brand names Altadiol, Deladiol, Delestrogen, Estraval, Lastrogen, Progynova, Valergen, many others), or oestradiol valerate (BAN), is a synthetic ester, specifically the 17-pentanoyl ester, of the natural estrogen, 17β-estradiol. It was first introduced, as Delestrogen by Squibb in the United States, in 1954, and along with estradiol benzoate (1936) and estradiol cypionate (1952), has since become one of the most widely used esters of estradiol.

基本信息

CAS:979-32-8
中文别名:17-戊酸-17-BETA-雌二酯;3-羟基雌甾-1,3,5(10)-三烯-17b-醇 17-戊酸酯;3,5(10)-三烯-17B-醇 17-戊酸酯;17-戊酸-Beta-雌二醇酯;17-戊酸-β-雌二醇酯;
英文别名:Estradiol valerate;
分子式:C23H32O3
分子量:356.498
精确质量:356.235
Psa:46.53
Logp:5.3503

编号系统

UNII:OKG364O896

物化性质

密度:1.13g/cm3
沸点:486.2ºC at 760mmHg
熔点:144°C
闪点:191.1ºC
折射率:1.567

安全信息

RTECS号:KG5793000
安全说明:S53-S45
危险类别码:R60; R61
WGK Germany:3
危险品标志:T

生产方法及用途

用途
用于治疗闭经、更年期综合症、减少乳汁分泌、前列腺癌等。

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图谱

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1H NMR : Predict


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