Cisatracurium (formerly recognized as 51W89, and marketed as Nimbex) is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is a bisbenzyltetrahydroisoquinolinium agent with an intermediate duration of action. Cisatracurium is one of the ten isomers of the parent molecule, atracurium. Moreover, cisatracurium represents approximately 15% of the atracurium mixture.

CAS：96946-42-8
中文别名：(1R,1\'R,2R,2\'R)-2,2\'-[1,5-戊二基双[氧(3-氧-3,1-丙二基)]]双[1-(3,4-二甲氧基苯基)甲基]-1,2,3,4-四氢-6,7-二甲氧基-2-甲基异喹啉]二苯磺酸盐;顺苯磺阿曲库铵;顺苯磺阿曲库铵(1R;顺苯阿曲库铵;
英文别名：Cisatracurium;cisatracurium besilate;Cis-AttacuriuM;(1R,1\'R,2R,2\'R);Cisatracurium besyla;Cisatrcurium Besylate;Cisatracurium bes (Cisatracuriumbesylate/Clotrimazole);(1R,1\'R)-atracurium besylate;Cisatracurium (besylate);1R,1R\'-2,2\'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl) methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium] dibenzenesulfonate;1 kg-1.5kg;Cisatracurium besylate;
分子式：C65H82N2O18S2
分子量：1243.48
精确质量：1242.5
Psa：257.6
Logp：11.3261

UNII：80YS8O1MBS

外观与性状：白色粉末
熔点：90-93ºC

海关编码：2914509090

用途
顺苯磺阿曲库铵（cisatracurium besylate）是最新一代肌松剂，与目前临床主要肌松麻醉药比较，本品具有通过非肝非肾途径代谢的特点和心血管稳定性，肌松作用比阿曲库铵作用强3倍，无心血管副作用。顺苯磺阿曲库铵主要适用于全身麻醉，并能广泛应用在气管插管、肝肾功能障碍、心血管手术及老年和儿科病人。该药自1996年在英国首次上市后，国外已逐渐代替维库溴铵和阿曲库铵，成为临床肌松药的主流。