8-Phenyltheophylline (8-Phenyl-1,3-dimethylxanthine, 8-PT) is a drug derived from the xanthine family which acts as a potent and selective antagonist for the adenosine receptors A1 and A2A, but unlike other xanthine derivatives has virtually no activity as a phosphodiesterase inhibitor. It has stimulant effects in animals with similar potency to caffeine. Coincidentally 8-phenyltheophylline has also been found to be a potent and selective inhibitor of the liver enzyme CYP1A2 which makes it likely to cause interactions with other drugs which are normally metabolised by CYP1A2.

CAS：961-45-5
中文别名：
英文别名：1,3-dimethyl-8-phenyl-3,7-dihydro-1H-purine-2,6-dione;1H-Purine-2,6-dione,2,3,6,7-tetrahydro-1,3-dimethyl-8-phenyl;8-Phenyltheophylline;1,3-dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione;Lopac-P-2278;1,3-dimethyl-8-phenyl-3,7-dihydro-purine-2,6-dione;Theophylline,8-phenyl;1,3-Dimethyl-8-phenylxanthine;1,3-dimethyl-7-phenylxanthine;
分子式：C13H12N4O2
分子量：256.26
精确质量：256.096
Psa：72.68
Logp：0.6273

MDL号：MFCD00005582

密度：1.361g/cm3
沸点：517.7ºC at 760mmHg
熔点：>300ºC(lit.)
闪点：266.9ºC
折射率：1.639

RTECS号：UO8445700
WGK Germany：3
海关编码：2933990090