PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias. PCI-34051 did not affect other hematopoietic or solid tumor lines. PCI-34051 treatment has been shown to significantly reduce cholesterol accumulation in Niemann-Pick type C1 gene mutated human fibroblast.

CAS：950762-95-5
中文别名：
英文别名：
分子式：C17H16N2O3
分子量：296.321
精确质量：296.116
Psa：63.49
Logp：3.2081

密度：1.3±0.1g/cm3
折射率：1.621
储存条件：2-8°C