Tamibarotene (brand name: Amnolake), also called retinobenzoic acid, is orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity against acute promyelocytic leukaemia (APL) . It is currently marketed only in Japan and early trials have demonstrated that it tends to be better tolerated than ATRA. It has also been investigated as a possible treatment for Alzheimer's disease, multiple myeloma and Crohn's disease.

CAS：94497-51-5
中文别名：TAMIBAROTENE,AM 80,AM-80,AM80;4-[(5,5,8,8-四甲基-6,7-二氢萘-2-基)氨基甲酰]苯甲酸;
英文别名：4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid;4-((5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl)benzoic acid;
分子式：C22H25NO3
分子量：351.439
精确质量：351.183
Psa：66.4
Logp：5.0591

MDL号：MFCD00866188

外观与性状：结晶固体
密度：1.154g/cm3
沸点：449.6ºC at 760mmHg
熔点：231-232ºC
闪点：225.7ºC
折射率：1.593

海关编码：2924299090