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化合物简介

Ibrutinib (USAN, also known as PCI-32765 and marketed under the name Imbruvica) is an anticancer drug targeting B-cell malignancies. It is an orally-administered, selective and covalent inhibitor of the enzyme Bruton's tyrosine kinase (BTK).

基本信息

CAS:936563-96-1
中文别名
英文别名:2-​Propen-​1-​one, 1-​[(3R)​-​3-​[4-​amino-​3-​(4-​phenoxyphenyl)​-​1H-​pyrazolo[3,​4-​d]​pyrimidin-​1-​yl]​-​1-​piperidinyl]​-;
分子式:C25H24N6O2
分子量:440.497
精确质量:440.196
Psa:99.16
Logp:4.7364

编号系统

MDL号:MFCD20261150

物化性质

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

1H NMR : Predict


13C NMR : Predict


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