DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models (1nM). DMOG also inhibits FIH (factor inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/Kg).

CAS：89464-63-1
中文别名：二甲基乙二酰氨基乙酸;
英文别名：methyl 2-[(2-methoxy-2-oxoethyl)amino]-2-oxoacetate;
分子式：C6H9NO5
分子量：175.139
精确质量：175.048
Psa：81.7
Logp：-1.1605

MDL号：MFCD05865098

密度：1.247g/cm3
熔点：46-48ºC
折射率：1.44
储存条件：Refrigerator

海关编码：2924199090
危险品标志：Xi
危险性描述：H302
信号词：Warning
危险标志：GHS07