化学科研者一站式服务平台


  • 7-甲氧基-1H-吲唑-3-羧酸甲酯

    methyl 7-methoxy-2H-indazole-3-carboxylate

化合物简介

Methyl 7-Methoxy-2H-indazole-3-carboxylate is an intermediate in the synthesis of 7-Hydroxy Granisetron, a metabolite of Granisetron, a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor.

基本信息

CAS:885278-95-5
中文别名
英文别名:1H-Indazole-3-carboxylicacid,7-methoxy-,methyl ester;METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE;
分子式:C10H10N2O3
分子量:206.198
精确质量:206.069
Psa:64.21
Logp:1.3581

编号系统

物化性质

安全信息

海关编码:2933990090

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


加载中...