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化合物简介
Methyl 7-Methoxy-2H-indazole-3-carboxylate is an intermediate in the synthesis of 7-Hydroxy Granisetron, a metabolite of Granisetron, a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor.
基本信息
CAS:885278-95-5
中文别名:
英文别名:1H-Indazole-3-carboxylicacid,7-methoxy-,methyl ester;METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE;
分子式:C10H10N2O3
分子量:206.198
精确质量:206.069
Psa:64.21
Logp:1.3581
中文别名:
英文别名:1H-Indazole-3-carboxylicacid,7-methoxy-,methyl ester;METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE;
分子式:C10H10N2O3
分子量:206.198
精确质量:206.069
Psa:64.21
Logp:1.3581
编号系统
物化性质
安全信息
海关编码:2933990090
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
