Tandospirone is a 5HT1A receptor partial agonist. Studies indicate that tandospirone significantly reduces haloperidol-induced bradykinesia in a dose dependent manner. The potency of Tandospirone is equal to that of buspirone and approximate one-half that of diazepam. The potency of Tandospirone at dopamine antagonistic action is less than 1/4 that of buspirone.

CAS：87760-53-0
中文别名：(3ΑΑ,4Β,7Β,7ΑΑ)-六氢-2-[4-[4-(2-嘧啶基)-1-哌嗪基]丁基]-4,7-亚甲基-1H-异吲哚-1,3(2H)-二酮;3A,4,7,7A-六氢-2-(4-(4-(2-嘧啶基)-1-哌嗪基)丁基)-4,7-甲桥-1H-异吲哚-1,3(2H)-二酮;
英文别名：[14C]-Tandospirone;
分子式：C21H29N5O2
分子量：383.487
精确质量：383.232
Psa：69.64
Logp：1.3507

密度：1.239g/cm3
沸点：613.9ºC at 760 mmHg
折射率：1.589
储存条件：Store at +4ºC

生产方法
原冰片烷和1-(4-氨基丁基)-4-(2-嘧啶基)哌嗪反应，即得产物。 5HT1A部分激动剂。用于治疗忧郁症。
用途
5HT1A部分激动剂。用于治疗忧郁症。