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5-([1,1’-联苯]-4-甲基)-N,N-二甲基-1H-四氮唑-1-甲酰胺
N,N-dimethyl-5-[(4-phenylphenyl)methyl]tetrazole-1-carboxamide
化合物简介
LY-2183240 is a drug which acts both as a potent inhibitor of the reuptake of the endocannabinoid anandamide and as an inhibitor of fatty acid amide hydrolase (FAAH), the primary enzyme responsible for degrading anandamide. This leads to markedly elevated anandamide levels in the brain, and LY-2183240 has been shown to produce both analgesic and anxiolytic effects in animal models. While LY-2183240 is a potent inhibitor of FAAH, it has relatively poor selectivity and also inhibits several other enzyme side targets. Consequently, it was never developed for clinical use, though it remains widely used in research, and has also been sold as a designer drug.
基本信息
CAS：874902-19-9
中文别名：5-([1,1\'-联苯]-4-甲基)-N,N-二甲基-1H-四氮唑-1-甲酰胺;
英文别名：HMS3269E15;1H-Tetrazole-1-carboxamide;
分子式：C17H17N5O
分子量：307.35
精确质量：307.143
Psa：63.91
Logp：2.4606
中文别名：5-([1,1\'-联苯]-4-甲基)-N,N-二甲基-1H-四氮唑-1-甲酰胺;
英文别名：HMS3269E15;1H-Tetrazole-1-carboxamide;
分子式：C17H17N5O
分子量：307.35
精确质量：307.143
Psa：63.91
Logp：2.4606
编号系统
UNII：2WBU91OKM7
物化性质
密度：1.22g/cm3
沸点：506.103ºC at 760 mmHg
熔点：87-88ºC
闪点：259.882ºC
折射率：1.64
储存条件：Store at +4ºC
沸点：506.103ºC at 760 mmHg
熔点：87-88ºC
闪点：259.882ºC
折射率：1.64
储存条件：Store at +4ºC
安全信息
危险类别码：R22
生产方法及用途
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上游原料
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图谱
Predict 1H proton NMR
13C NMR : Predict
1H NMR : Predict
