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化合物简介
Homatropine (Equipin, Isopto Homatropine) is an anticholinergic medication that is an antagonist at muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic (to temporarily paralyze accommodation), and as a mydriatic (to dilate the pupil). For Homatropine methylbromide see Methylhomatropine, this is a different medication. Homatropine is less potent than atropine and has a shorter duration of action. It is available as the hydrobromide salt.
基本信息
CAS：87-00-3
中文别名：扁桃酰托品碱;8-甲基-8-氮杂双环[3.2.1]辛烷-3-醇羟基(苯基)乙酸酯;
英文别名：Omatropina [DCIT];Homatropin;Homotropine;DL-mandelic acid-tropane-3endo-yl ester;Homoatropine;homatropine;Mandelyltropeine;Homatropine [BAN];Benzeneacetic acid, α-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-(±)-;Methylhomatropinum;homatropine hydrobromide;8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester;DL-Mandelsaeure-tropan-3endo-ylester;Mandelytropeine;
分子式：C16H21NO3
分子量：275.343
精确质量：275.152
Psa：49.77
Logp：1.8263
中文别名：扁桃酰托品碱;8-甲基-8-氮杂双环[3.2.1]辛烷-3-醇羟基(苯基)乙酸酯;
英文别名：Omatropina [DCIT];Homatropin;Homotropine;DL-mandelic acid-tropane-3endo-yl ester;Homoatropine;homatropine;Mandelyltropeine;Homatropine [BAN];Benzeneacetic acid, α-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-(±)-;Methylhomatropinum;homatropine hydrobromide;8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester;DL-Mandelsaeure-tropan-3endo-ylester;Mandelytropeine;
分子式：C16H21NO3
分子量：275.343
精确质量：275.152
Psa：49.77
Logp：1.8263
编号系统
UNII：8QS6WCL55Z
物化性质
密度：1.21 g/cm3
沸点：403.3ºC
熔点：100ºC
闪点：197.7ºC
沸点：403.3ºC
熔点：100ºC
闪点：197.7ºC
安全信息
海关编码：2933990090
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
Mass spectrum (electron ionization)
