Neurokinin B (NKB) belongs in the family of tachykinin peptides. Neurokinin B is implicated in a variety of human functions and pathways such as the secretion of gonadotropin-releasing hormone. Additionally, NKB is associated with pregnancy in females and maturation in young adults. Reproductive function is highly dependent on levels of both neurokinin B and also the G-protein coupled receptor ligand kisspeptin. The first NKB studies done attempted to resolve why high levels of the peptide may be implicated in pre-eclampsia during pregnancy. NKB, kisspeptin, and dynorphin together are found in the arcuate nucleus (ARC) known as the KNDy subpopulation. This subpopulation is targeted by a large number of steroid hormones and works to form a network that feeds back to GnRH pulse generator.

CAS：86933-75-7
中文别名：β-Neurokinin;
英文别名：NEUROMEDIN K;NEUROKININ B;NEUROKININ K;Neurokinin B NKB;NKB;DMHDFFVGLM-NH2;
分子式：C55H79N13O14S2
分子量：1210.42
精确质量：1209.53
Psa：484.89
Logp：3.3212

MDL号：MFCD00133665
PubChem号：24897694

密度：1.313 g/cm3
沸点：1646ºC at 760 mmHg
闪点：949.3ºC
折射率：1.591
储存条件：-20ºC