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  • (5R)-5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-N-(1-piperidinyl)- 4,5-dihydro-1H-pyrazole-3-carboxamide

化合物简介

Rosonabant (INN; E-6776) is a drug acting as a CB1 receptor antagonist/inverse agonist that was under investigation by Esteve as an appetite suppressant for the treatment of obesity. Development of the drug for clinical use was apparently halted shortly after the related CB1 antagonist rimonabant was discontinued, likely due to the reports of severe psychiatric adverse effects such as anxiety, depression, and suicidal ideation associated with it and with similarly-acting agents.

基本信息

CAS:861151-12-4
中文别名
英文别名
分子式:C21H21Cl3N4O
分子量:451.777
精确质量:450.078
Psa:47.94
Logp:5.3007

编号系统

UNII:7X5RY2T485

物化性质

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


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