Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Blebbistatin also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. Blebbistatin blocks both blebbing and cytokinesis at 50-100µM.\n[Blebbistatin:a]D= -103 (c= 1.21 CHCl3)\n(-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-one\n\nBlebbistatin is a selective inhibitor of nonmuscle myosin II; Blebbistatin inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Blebbistatin rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells.

CAS：856925-71-8
中文别名：
英文别名：(3aS)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one;
分子式：C18H13N2O2
分子量：289.308
精确质量：289.098
Psa：52.9
Logp：1.6105

MDL号：MFCD08460907

熔点：210-212ºC
储存条件：Desiccate at +4ºC

危险标志：GHS07
信号词：Warning
危险性防范说明：P261; P280; P305 + P351 + P338
危险性描述：H302; H312; H315; H317; H319; H332; H335