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  • 猪去氧胆酸

    hyodeoxycholic acid

化合物简介

Hyodeoxycholic acid, also known as 3α,6α-Dihydroxy-5β-cholan-24-oic acid or HDCA, is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria. It differs from deoxycholic acid in that the 6α-hydroxyl is in the 12 position in the former. The 6α-hydroxyl group makes HDCA a hydrophilic acid, a property it shares with hyocholic acid. HDCA is present in mammalian species in different proportions. It is the main acid constituent of hog bile, and for this reason it was used industrially as precursor for steroid synthesis before total synthesis became practical.

基本信息

CAS:83-49-8
中文别名:猪脱氧胆酸;3α,6α-二羟基-5β-胆烷酸;
英文别名:Hyodeoxycholic;Iodeoxycholic acid;Cholan-24-oic acid, 3,6-dihydroxy-, (3α,5β,6α)-;HYODEOXYCHOLANIC ACID;HYODESOXYCHOLIC ACID;HYDROCHOLIC ACID;HDCA;Pig deoxybile acid;Hyodeoxycholic acid;7-deoxyhyocholicacid;
分子式:C24H40O4
分子量:392.572
精确质量:392.293
Psa:77.76
Logp:4.4779

编号系统

MDL号:MFCD00003681

物化性质

外观与性状:本品是由猪胆汁中提取的一种胆烷酸,为白色或略带微黄色粉末,臭且微腥、味苦。Mp 197℃(分解)。略溶于醇,在丙酮中微溶,在乙醚、氯仿中极微溶,几乎不溶于水。 本品能抑制胆酸的形成及溶解脂肪,降低血中胆固醇和甘油三酯。
熔点:200-201°C(lit.)

安全信息

RTECS号:FZ2050000
安全说明:S26; S36/37/39; S36; S22
危险类别码:R36/37/38; R40
WGK Germany:3
危险品标志:Xn

生产方法及用途

生产方法
1. 1.用于生化研究。
用途
1.用于生化研究。

合成路线

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图谱

1H NMR : Predict


13C NMR : Predict


13C NMR : in DMSO-d6


Mass


IR : nujol mull


IR : KBr disc


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