8-Anilinonaphthalene-1-sulfonic acid (ANS), also called 1-anilino-8-naphthalenesulfonate, is an organic compound containing both a sulfonic acid and an amine group. This compound is used as a fluorescent molecular probe. For example, ANS can be used to study conformational changes induced by ligand binding in proteins, as ANS's fluorescent properties will change as it binds to hydrophobic regions on the protein surface. Comparison of the fluorescence in the presence and absence of a particular ligand can thus give information about how the binding of the ligand changes the surface of the protein. Its permeability to mitochondrial membranes makes it particularly useful.

CAS：82-76-8
中文别名：N-苯基-1-萘胺-8-磺酸;苯基周位酸;N-苯基周位酸;
英文别名：8-Anilino-1-naphthalenesulfonic Acid;8-Anilino-1-naphthalenesulfonic acid;
分子式：C16H13NO3S
分子量：299.344
精确质量：299.062
Psa：74.78
Logp：4.9839

MDL号：MFCD00003998

外观与性状：灰色至绿色潮湿的粉末
密度：1.41 g/cm3
熔点：215-217°C (dec.)(lit.)
稳定性：Stable under normal temperatures and pressures.
储存条件：Store in a cool, dry place. Store in a tightly closed container.

安全说明：S26
WGK Germany：-
危险类别码：R36
海关编码：29214980
危险品标志：Xi

生产方法
由苯胺和周位酸在硫酸存在下缩合而得。缩合反应物减压蒸馏可得精制的N-苯基周位酸。将其与纯碱反应，水蒸气蒸馏，活性炭脱色，即得N-苯基周位酸。 染料中间体。
用途
染料中间体。