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 (±)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole
 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)piperidin-4-ol
化合物简介
                L-741,626 is a drug which acts as a potent and selective antagonist for the dopamine receptor D2. It has good selectivity over the related D3 and D4 subtypes and other receptors. L-741,626 is used for laboratory research into brain function and has proved particularly useful for distinguishing D2 mediated responses from those produced by the closely related D3 subtype, and for studying the roles of these subtypes in the action of cocaine and amphetamines in the brain.
            
            基本信息
                CAS:81226-60-0
中文别名:
英文别名:4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol;L 741,626;1-(indol-3-ylmethyl)-4-hydroxy-4-(p-chlorophenyl)piperidine;4-Piperidinol,4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl);3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole;
分子式:C20H21ClN2O
分子量:340.847
精确质量:340.134
Psa:39.26
Logp:4.2428
            中文别名:
英文别名:4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol;L 741,626;1-(indol-3-ylmethyl)-4-hydroxy-4-(p-chlorophenyl)piperidine;4-Piperidinol,4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl);3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole;
分子式:C20H21ClN2O
分子量:340.847
精确质量:340.134
Psa:39.26
Logp:4.2428
编号系统
物化性质
                                    密度:1.311g/cm3
沸点:548.8ºC at 760 mmHg
闪点:285.7ºC
折射率:1.686
                            
            沸点:548.8ºC at 760 mmHg
闪点:285.7ºC
折射率:1.686
安全信息
生产方法及用途
合成路线
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                            参考文献John Wyeth and Brother Limited Patent: US4358456 A1, 1982 ; 
上游原料
下游产品
图谱
13C NMR : Predict
 
                1H NMR : Predict
 
                



