Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract. It acts directly as a serotonin 5-HT4 receptor agonist and indirectly as a parasympathomimetic. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. It has been sold under the trade names Prepulsid (Janssen-Ortho) and Propulsid (in the United States). It was discovered by Janssen Pharmaceutica in 1980. In many countries, it has been either withdrawn from the market or had its indications limited because of side-effects.

CAS：81098-60-4
中文别名：西沙必利;
英文别名：Alimix;CIPRIL;prepulsid;propulsid;ACENALIN;Risamol;Cisapride;Risamal;
分子式：C23H29ClFN3O4
分子量：465.945
精确质量：465.183
Psa：86.05
Logp：4.2681

UNII：UVL329170W

外观与性状：白色至略米色粉末
密度：1.29 g/cm3
沸点：605.4ºC at 760 mmHg
熔点：107 - 111ºC
闪点：319.9ºC
折射率：1.593
储存条件：Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

RTECS号：CU9372000
安全说明：S26-S39
危险类别码：R41
WGK Germany：2
海关编码：2942000000
危险品标志：Xi

生产方法
3-甲氧基-4-氨基哌啶和4-乙酰氨基-2-甲氧基-5-氯苯甲酸脱水酰胺化,生成4-乙酰氨基-2-甲氧-5-氯-N-(3-甲氧基-4-哌啶基)苯甲酰胺,再和对氟苯氯丙醚进行氮上的烷基化反应,酸化水解生成西沙必利。 1.胃肠动力药，能加强并协调胃肠道运动，防止食物的滞留及反流，因而有止吐效果。
用途
1.胃肠动力药，能加强并协调胃肠道运动，防止食物的滞留及反流，因而有止吐效果。