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依度孕酮
(8R,9S,10R,13S,14S,17R)-17-Acetyl-6,10,13-trimethyl-1,2,4,7,8,9,1 0,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthr ene-3,2'-[1,3]dioxolan]-17-yl acetate
化合物简介
Edogestrone (INN, BAN) (developmental code name PH-218), or edogesterone, also known as 17α-acetoxy-3,3-ethylenedioxy-6-methyl-5-pregnen-20-one, is a steroidal progestin and antiandrogen of the 17α-hydroxyprogesterone group that was synthesized in 1964 but was never marketed. Similarly to the structurally related steroid cyproterone acetate, edogestrone binds directly to the androgen receptor and displaces androgens like testosterone from it, though not as potently. The drug also suppresses androgen production.
基本信息
CAS：809-01-8
中文别名：
英文别名：19-norpregn-4-ene-3,20-dione,17-(acetyloxy);17-Acetoxy-3-ethylendioxy-6-methyl-pregn-5-en-20-on;19-Nor-17alpha-hydroxyprogesterone acetate;17-acetoxy-19-nor-pregn-4-ene-3,20-dione;Gestonoronacetat;17-Acetoxy-19-nor-pregn-4-en-3,20-dion;
分子式：C26H38O5
分子量：430.577
精确质量：430.272
Psa：61.83
Logp：4.9733
中文别名：
英文别名：19-norpregn-4-ene-3,20-dione,17-(acetyloxy);17-Acetoxy-3-ethylendioxy-6-methyl-pregn-5-en-20-on;19-Nor-17alpha-hydroxyprogesterone acetate;17-acetoxy-19-nor-pregn-4-ene-3,20-dione;Gestonoronacetat;17-Acetoxy-19-nor-pregn-4-en-3,20-dion;
分子式：C26H38O5
分子量：430.577
精确质量：430.272
Psa：61.83
Logp：4.9733
编号系统
UNII：9014UFK50C
物化性质
密度：1.16g/cm3
沸点：518.2ºC at 760 mmHg
闪点：247.9ºC
折射率：1.547
沸点：518.2ºC at 760 mmHg
闪点：247.9ºC
折射率：1.547
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
