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化合物简介

Solanidine is a poisonous steroidal alkaloid chemical compound that occurs in plants of the Solanaceae family, such as potato and Solanum americanum. Human ingestion of solanidine also occurs via the consumption of the glycoalkaloids, α-solanine and α-chaconine, present in potatoes. The sugar portion of these glycoalkaloids hydrolyses in the body, leaving the solanidine portion. Solanidine occurs in the blood serum of normal healthy people who eat potato, and serum solanidine levels fall markedly once potato consumption ceases. Solanidine from food is also stored in the human body for prolonged periods of time, and it has been suggested that it could be released during times of metabolic stress with the potential for deleterious consequences. Solandine is responsible for neuromuscular syndromes via cholinesterase inhibition.

基本信息

CAS:80-78-4
中文别名:茄啶;
英文别名:Solanid-5-en-3beta-ol;Solanidine;Solanidin;Solatubin;Solatubine;22R,25S-Solanidanine;
分子式:C27H43NO
分子量:397.636
精确质量:397.334
Psa:23.47
Logp:5.5929

编号系统

UNII:W7801OHM8B

物化性质

密度:1.1g/cm3
沸点:503.1ºC at 760 mmHg
熔点:212-214ºC
闪点:223.5ºC
折射率:1.576
储存条件:2-8ºC

安全信息

安全说明:S2-S13-S22-S45-S36-S37-S39
危险类别码:R23/24/25
危险品运输编码:UN 1544
危险类别:6.1(b)
包装等级:III
危险品标志:T+

生产方法及用途

生产方法
可通过茄碱水解获得,也可人工合成。 用于生化研究。
用途
用于生化研究。

合成路线

  • 参考文献

    Samikov, K.; Rashkes, Ya. V.; Shakirov, R.; Yunusov, S. Yu. Chemistry of Natural Compounds, 1981 , vol. 17, p. 273 - 278 Khimiya Prirodnykh Soedinenii, 1981 , vol. 17, # 3 p. 349 - 356

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图谱

13C NMR : Predict


1H NMR : Predict


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