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化合物简介
Segesterone acetate (USAN) (brand name Nestorone; former developmental code names ST-1435, AC-6844, CS-0411), known more commonly simply as nestorone (or nestoron) and also known as elcometrine, is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries. Nestorone is the acetate ester of segesterone, which was never marketed, but is an active metabolite of nestorone. Nestorone is only weakly active orally, and is instead given as a subcutaneous implant. It is more than 100-fold times as potent when delivered subcutaneously relative to orally.
基本信息
CAS:7759-35-5
中文别名:
英文别名:19-Norpregn-4-ene-3,20-dione,17-hydroxy-16-methylene-,acetate;NESTORONE;17-(ACETYLOXY)-16-METHYLENE-19-NORPREGN-4-ENE-20-DIONE;16-Methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione acetate;Elcometrine;17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate;
分子式:C23H30O4
分子量:370.482
精确质量:370.214
Psa:60.44
Logp:4.1852
中文别名:
英文别名:19-Norpregn-4-ene-3,20-dione,17-hydroxy-16-methylene-,acetate;NESTORONE;17-(ACETYLOXY)-16-METHYLENE-19-NORPREGN-4-ENE-20-DIONE;16-Methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione acetate;Elcometrine;17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate;
分子式:C23H30O4
分子量:370.482
精确质量:370.214
Psa:60.44
Logp:4.1852
编号系统
UNII:9AMX4Q13CC
物化性质
密度:1.15g/cm3
沸点:499.3ºC at 760mmHg
闪点:216.2ºC
折射率:1.549
沸点:499.3ºC at 760mmHg
闪点:216.2ºC
折射率:1.549
安全信息
生产方法及用途
合成路线
上游原料
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图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict
