Sitagliptin intermediate. A dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension.

CAS：767340-03-4
中文别名：(2Z)-4-氧代-4-[3-(三氟甲基)-5,6-二氢-[1,2,4]三唑并[4,3-A]吡嗪-7(8H)-基]-1-(2,4,5-三氟苯基)-2-丁烯胺;(2Z)-2-氨基-4-氧-4-[3-(三氟甲基)-5,6-二氢[1,2,4]三唑[4,3-Α]吡嗪-7(8H)-基]-1-(2,4,5-三氟苯基)丁基-2-烯(2-4);西他列汀烯胺杂质;7(8H)-基]-1-(245-三氟苯基)丁-2-烯-2-胺;
英文别名：2-Buten-1-ol,4-[[(1,1-dimethylethyl)dimethylsilyl]oxy];2-Buten-1-ol,4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-,(Z);(2Z)-4-{[tert-butyl(dimethyl)silyl]oxy}but-2-en-1-ol;(2Z)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-en-2-amine;(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine;(Z)-4-(tert-butyl-dimethyl-silanyloxy)-but-2-en-1-ol;(Z)-3-amino-1-(3-trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one;(Z)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]-pyrazyn-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one;cis-4-(1,1,2,2-tetramethyl-1-silapropoxy)but-2-en-1-ol;(2Z)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine;(2Z)-4-(tert-butyldimethylsilanyloxy)but-2-en-1-ol;cis-4-(tert-butyldimethylsilanyloxy)-but-2-en-1-ol;
分子式：C16H13F6N5O
分子量：405.298
精确质量：405.102
Psa：77.04
Logp：2.7799

MDL号：MFCD12031551

密度：1.6 g/cm3
沸点：555.1ºC at 760 mmHg
熔点：178-180ºC
折射率：1.59
储存条件：Refrigerator

海关编码：2933990090