Perfluorooctanesulfonamide (PFOSA) is a synthetic organofluorine compound. It is a fluorocarbon derivative and a perfluorinated compound, having an eight-carbon chain and a terminal sulfonamide functional group. PFOSA, a persistent organic pollutant, was an ingredient in 3M's former Scotchgard formulation from 1956 until 2003, and the compound was used to repel grease and water in food packaging along with other consumer applications. It breaks down to form perfluorooctane sulfonate (PFOS). The perfluorooctanesulfonyl fluoride-based chemistry that was used to make sulfonamides like PFOSA was phased out by 3M in the United States (US) during 2000–2002 but it has grown in China by other producers.

CAS：754-91-6
中文别名：FC-99;全氟辛烷磺酰胺;
英文别名：1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane-1-sulfonamide;
分子式：C8H2F17NO2S
分子量：499.145
精确质量：498.953
Psa：68.54
Logp：6.0229

EINECS号：212-046-0

外观与性状：透明液体
密度：1.793 g/cm3
沸点：227.2ºC at 760 mmHg
闪点：91.2ºC
折射率：1.309

安全说明：S22-S24/25
海关编码：2942000000
危险品标志：Xi

用途
全氟辛基磺酰胺用于合成氟表面活性剂，用于引入其它基团至氮原子上。