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  • 3-氨基巴豆酸乙酯

    3-Amino-2-butenoic acid ethyl ester

化合物简介

Ethyl 3-Aminocrotonate is used as a reagent to synthesize Nitrendipine, a calcium channel antagonist that is used to treat patients with hypertension. Ethyl 3-Aminocrotonate is also used as a reagent to synthesize (S)-Felodipine, a calcium entry blocker that has antihypertensive properties.

基本信息

CAS:7318-00-5
中文别名:3-氨基-2-丁烯酸乙酯;乙基-3-氨基丁烯酸酯;
英文别名:ETHYL 3-AMINO-2-BUTENOATE;2-Butenoic acid, 3-amino-, ethyl ester;3-Amino-2-butenoic acid ethyl;Ethyl 3-Amino-2-butanol;ETHYL B-IMINOBUTYRATE;
分子式:C6H11NO2
分子量:129.157
精确质量:129.079
Psa:52.32
Logp:1.1123

编号系统

MDL号:MFCD00008073
EINECS号:230-782-0

物化性质

外观与性状:略黄色低熔点固体或液体
密度:1.022g/mLat 25°C(lit.)
沸点:210-215°C(lit.)
熔点:33-35°C(lit.)
闪点:207°F
折射率:1.5-1.502
稳定性:Stable under normal temperatures and pressures.
储存条件:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.

安全信息

安全说明:S26-S27-S28-S36/37/39-S45
危险类别码:R34; R36/37
WGK Germany:3
危险品运输编码:UN 3263 8/PG 2
包装等级:I; II; III
危险品标志:C

生产方法及用途

合成路线

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


13C NMR : in CDCl3


13C NMR : in CDCl3


1H NMR : 90 MHz in CDCl3


1H NMR : in CDCl3


Mass


IR : nujol mull


IR : liquid film


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