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化合物简介

Otenabant (CP-945,598) is a drug which acts as a potent and highly selective CB1 antagonist. It was developed by Pfizer for the treatment of obesity, but development for this application has been discontinued following the problems seen during clinical use of the similar drug rimonabant.

基本信息

CAS:686344-29-6
中文别名:1-[9-(4-氯苯基)-8-(2-氯苯基)-9H-嘌呤-6-基]-4-乙基氨基哌啶-4-甲酰胺;
英文别名:otenabant;CP-945,598;UNII-J8211Y53EF;1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-(ethylamino)piperidine-4-carboxamide;
分子式:C25H25Cl2N7O
分子量:510.418
精确质量:509.15
Psa:101.96
Logp:5.3793

编号系统

UNII:J8211Y53EF

物化性质

密度:1.46
沸点:757.891ºC at 760 mmHg

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

1H NMR : Predict


13C NMR : Predict


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