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化合物简介
Dimethyliodoarsine is a dimethylated metabolite of Arsenic Trioxide that acts as a more potent growth inhibitor and apoptotic inducer in NB4 cells, an APL cell line. Dimethyliodoarsine is an arsenite metabolite in wild type CHO cells and in cells deficient in excision repair cross-complementing 1 and 2. Dimethyliodoarsine is also an inhibitor of Thioredoxin reductase, an enzyme involved in the response of the cell to oxidative stress.
基本信息
CAS:676-75-5
中文别名:
英文别名:iodo(dimethyl)arsane;
分子式:C2H6AsI
分子量:231.895
精确质量:231.873
Psa:0.0
Logp:1.6725
中文别名:
英文别名:iodo(dimethyl)arsane;
分子式:C2H6AsI
分子量:231.895
精确质量:231.873
Psa:0.0
Logp:1.6725
编号系统
EINECS号:211-630-2
物化性质
沸点:133.4ºC at 760 mmHg
闪点:45.1ºC
闪点:45.1ºC
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
