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化合物简介

GW-842,166X is a drug which acts as a potent and selective cannabinoid CB2 receptor agonist, with a novel chemical structure based on a pyrimidine core. It has potent analgesic, anti-inflammatory and anti-hyperalgesic actions in animal models, but without cannabis-like behavioural effects due to its extremely low affinity for the CB1 receptor.

基本信息

CAS:666260-75-9
中文别名
英文别名:2-(2,4-dichloroanilino)-N-(oxan-4-ylmethyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide;UNII-VL1I6P2DZ8;
分子式:C18H17Cl2F3N4O2
分子量:449.254
精确质量:448.068
Psa:76.14
Logp:5.1661

编号系统

UNII:VL1I6P2DZ8

物化性质

密度:1.4±0.1g/cm3
折射率:1.571
储存条件:-20°C

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

1H NMR : Predict


13C NMR : Predict


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