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  • 维甲酰酚胺

    4-hydroxyphenyl retinamide

化合物简介

Fenretinide (4-hydroxy(phenyl)retinamide; 4-HPR) (INN) is a synthetic retinoid derivative. Retinoids are substances related to vitamin A. It has been investigated for potential use in the treatment of cancer, as well as in the treatment of cystic fibrosis, rheumatoid arthritis, acne, psoriasis, and has been found to also slow the production and accumulation of a toxin that leads to vision loss in Stargardt's patients.

基本信息

CAS:65646-68-6
中文别名:酚维A胺;维甲酸对羟基苯胺;芬维A胺;全反式-N-(4-羟苯基)维甲酸;
英文别名:Fenretinide(4-HPR);
分子式:C26H33NO2
分子量:391.546
精确质量:391.251
Psa:49.33
Logp:6.9353

编号系统

UNII:187EJ7QEXL

物化性质

外观与性状:黄色粉末
密度:1.081 g/cm3
沸点:597.6ºC at 760 mmHg
熔点:162-163°C
闪点:315.2ºC
折射率:1.607
稳定性:Light Sensitive - Protect from Light Exposure
储存条件:-20ºC

安全信息

RTECS号:VH6420000
安全说明:S53-S26-S36/37/39-S45
WGK Germany:3
危险类别码:R60; R61; R20/21/22; R36/37/38
危险品标志:T
危险标志:GHS07, GHS08
信号词:Danger
危险性描述:H302 + H312 + H332; H315; H319; H335; H360
危险性防范说明:P201; P261; P280; P305 + P351 + P338; P308 + P313

生产方法及用途

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图谱

Predict 1H proton NMR


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