Ubenimex (INN), also known more commonly as bestatin, is a competitive, reversible protease inhibitor. It is an inhibitor of arginyl aminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (a zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities), alanyl aminopeptidase (aminopeptidase M/N), leucyl/cystinyl aminopeptidase (oxytocinase/vasopressinase), and membrane dipeptidase (leukotriene D4 hydrolase). It is being studied for use in the treatment of acute myelocytic leukemia. It is derived from Streptomyces olivoreticuli. Ubenimex has been found to inhibit the enzymatic degradation of oxytocin, vasopressin, enkephalins, and various other peptides and compounds.

CAS：65391-42-6
中文别名：N-[(2S,3R)-3-氨基-2-羟基-4-苯基丁酰基]-L-亮氨酸盐酸盐;盐酸乌苯美司;盐酸贝他定;贝他定盐酸;盐酸倍他定;N-[(2S,3R)-3-氨基-2-羟基-4苯基丁]-L-亮氨酸盐酸盐;
英文别名：BESTATIN HYDROCHLORIDE;
分子式：C16H25ClN2O4
分子量：344.834
精确质量：344.15
Psa：112.65
Logp：2.426

EINECS号：613-790-2

沸点：604.7ºC at 760 mmHg
熔点：216-218°C
闪点：319.5ºC
储存条件：-20ºC

安全说明：S22; S24/25; S36; S26
危险类别码：R20/21/22
WGK Germany：3
海关编码：29242995
危险品标志：Xn