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  • 17α-二氢马烯雌酮

    17α-Dihydroequilin

化合物简介

17α-Dihydroequilin, or α-dihydroequilin, also known as estra-1,3,5(10),7-tetraene-3,17α-diol, is a natural estrogen found in horses that is closely related to equilin and equilenin. The compound, as the sodium salt of its sulfate ester, is present in the pharmaceutical drug Premarin, a conjugated estrogenic extract of the urine of pregnant mares, and is the third highest quantity constituent in the formulation (13.8%).

基本信息

CAS:651-55-8
中文别名:17α-二氢马烯雌甾酮;
英文别名:7-Dehydro-17α-estradiol;Estra-1,3,5(10),7-tetraen-3,17α-diol;(9S,13S,14S,17R)-13-methyl-6,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthrene-3,17-diol;α-dihydroequilin;α-Equilol;Estra-1,3,5(10),7-tetraene-3,17-diol, (17α)-;(17α)-Estra-1,3,5(10),7-tetraene-3,17-diol;
分子式:C18H22O2
分子量:270.366
精确质量:270.162
Psa:40.46
Logp:3.5293

编号系统

UNII:48P73794OJ

物化性质

密度:1.23g/cm3
沸点:457.798ºC at 760 mmHg
闪点:217.155ºC
折射率:1.637

安全信息

生产方法及用途

合成路线

  • 参考文献

    Journal of Biological Chemistry, , vol. 185, p. 267,269

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图谱

13C NMR : Predict


1H NMR : Predict


Mass spectrum (electron ionization)


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