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化合物简介
17α-Dihydroequilin, or α-dihydroequilin, also known as estra-1,3,5(10),7-tetraene-3,17α-diol, is a natural estrogen found in horses that is closely related to equilin and equilenin. The compound, as the sodium salt of its sulfate ester, is present in the pharmaceutical drug Premarin, a conjugated estrogenic extract of the urine of pregnant mares, and is the third highest quantity constituent in the formulation (13.8%).
基本信息
CAS:651-55-8
中文别名:17α-二氢马烯雌甾酮;
英文别名:7-Dehydro-17α-estradiol;Estra-1,3,5(10),7-tetraen-3,17α-diol;(9S,13S,14S,17R)-13-methyl-6,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthrene-3,17-diol;α-dihydroequilin;α-Equilol;Estra-1,3,5(10),7-tetraene-3,17-diol, (17α)-;(17α)-Estra-1,3,5(10),7-tetraene-3,17-diol;
分子式:C18H22O2
分子量:270.366
精确质量:270.162
Psa:40.46
Logp:3.5293
中文别名:17α-二氢马烯雌甾酮;
英文别名:7-Dehydro-17α-estradiol;Estra-1,3,5(10),7-tetraen-3,17α-diol;(9S,13S,14S,17R)-13-methyl-6,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthrene-3,17-diol;α-dihydroequilin;α-Equilol;Estra-1,3,5(10),7-tetraene-3,17-diol, (17α)-;(17α)-Estra-1,3,5(10),7-tetraene-3,17-diol;
分子式:C18H22O2
分子量:270.366
精确质量:270.162
Psa:40.46
Logp:3.5293
编号系统
UNII:48P73794OJ
物化性质
密度:1.23g/cm3
沸点:457.798ºC at 760 mmHg
闪点:217.155ºC
折射率:1.637
沸点:457.798ºC at 760 mmHg
闪点:217.155ºC
折射率:1.637
安全信息
生产方法及用途
合成路线
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参考文献
Journal of Biological Chemistry, , vol. 185, p. 267,269
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
Mass spectrum (electron ionization)


