Urapidil is a sympatholytic antihypertensive drug. It acts as an α1-adrenoceptor antagonist and as an 5-HT1A receptor agonist Although an initial report suggested that urapidil was also an α2-adrenoceptor agonist, this was not substantiated in later studies that demonstrated it was devoid of agonist actions in the dog saphenous vein and the guinea-pig ileum. Unlike some other α1-adrenoceptor antagonists, urapidil does not elicit reflex tachycardia, and this may be related to its weak β1-adrenoceptor antagonist activity, as well as its effect on cardiac vagal drive. Urapidil is currently not approved by the U.S. Food and Drug Administration, but it is available in Europe.

CAS：64887-14-5
中文别名：
英文别名：6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3-dimethylpyrimidine-2,4-dione,hydrochloride;
分子式：C20H30ClN5O3
分子量：423.937
精确质量：423.204
Psa：71.74
Logp：1.5947

UNII：PVU92PZO12

外观与性状：白色或灰白色结晶粉末
沸点：549ºC at 760 mmHg
熔点：156-158ºC
闪点：285.8ºC
储存条件：Desiccate at RT

RTECS号：YQ9862000
安全说明：S36
危险类别码：R22
WGK Germany：3
海关编码：3004909090
危险品标志：Xn