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化合物简介
The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
基本信息
CAS:636-61-3
中文别名:D(+)-苹果酸;(R)-羟基丁二酸;D-苹果酸;
英文别名:D-malate;(R)-2-Hydroxysuccinic acid;(2R)-2-hydroxybutanedioic acid;Butanedioic acid, hydroxy-, (R)-;2(R)-hydroxybutanedioic acid;Malic acid,D;D-(+)-malic acid;L-malic acid;D-(+)-Malic Acid;
分子式:C4H6O5
分子量:134.087
精确质量:134.022
Psa:94.83
Logp:-1.0934
中文别名:D(+)-苹果酸;(R)-羟基丁二酸;D-苹果酸;
英文别名:D-malate;(R)-2-Hydroxysuccinic acid;(2R)-2-hydroxybutanedioic acid;Butanedioic acid, hydroxy-, (R)-;2(R)-hydroxybutanedioic acid;Malic acid,D;D-(+)-malic acid;L-malic acid;D-(+)-Malic Acid;
分子式:C4H6O5
分子量:134.087
精确质量:134.022
Psa:94.83
Logp:-1.0934
编号系统
MDL号:MFCD00064212
EINECS号:210-514-9
EINECS号:210-514-9
物化性质
外观与性状:白色粉末
密度:1.6
沸点:322ºC
熔点:98-104ºC
闪点:153.4ºC
稳定性:Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
密度:1.6
沸点:322ºC
熔点:98-104ºC
闪点:153.4ºC
稳定性:Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
安全信息
安全说明:S26-S37/39
危险类别码:R36/37/38
海关编码:29181980
危险品标志:Xi
危险标志:GHS05, GHS07
信号词:Danger
危险性描述:H315; H318; H335
危险性防范说明:P261; P280; P305 + P351 + P338
危险类别码:R36/37/38
海关编码:29181980
危险品标志:Xi
危险标志:GHS05, GHS07
信号词:Danger
危险性描述:H315; H318; H335
危险性防范说明:P261; P280; P305 + P351 + P338
生产方法及用途
合成路线
-
参考文献
Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Patent: US6677476 B1, 2004 ; Location in patent: Page column 9 ;
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
IR : KBr disc













