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  • 甲烷三羧酸三乙酯

    Triethyl methanetricarboxylate

化合物简介

Triethyl Methanetricarboxylate is used in the synthesis of novel inhibitors of Hsp90. It is also used in the preparation of novel dihydroquinoline-3-carboxylic acids that function as HIV-1 integrase inhibitors.

基本信息

CAS:6279-86-3
中文别名:三羧酸甲烷三乙酯;甲烷三甲酸三乙酯;
英文别名:Methanetricarboxylic acid, triethyl ester;2-Ethoxycarbonyl-malonic acid diethyl ester;Diethyl 2-(ethoxycarbonyl)malonate;Carboxymalonic Acid Triethyl Ester;tricarbethoxymethane;Methanetricarboxylic acid,triethyl ester;Triethylmethanetricarboxylate;tri(ethoxycarbonyl)methane;
分子式:C10H16O6
分子量:232.23
精确质量:232.095
Psa:78.9
Logp:0.2919

编号系统

EINECS号:228-477-2
MDL号:MFCD00009150

物化性质

外观与性状:在熔点后,透明无色固体
密度:1.095g/mLat 25°C(lit.)
沸点:253°C(lit.)
熔点:25-26°C(lit.)
闪点:>230°F
折射率:n20/D 1.424(lit.)
水溶解性:immiscible
稳定性:Stable under normal temperatures and pressures.
储存条件:Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

安全信息

安全说明:S23-S24/25
WGK Germany:3
海关编码:29171990

生产方法及用途

用途
用作盐酸罗沙替丁醋酸酯中间体 医药中间体。

合成路线

上游原料

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图谱

13C NMR : Predict


1H NMR : Predict


13C NMR : in CDCl3


1H NMR : 400 MHz in CDCl3


Mass spectrum (electron ionization)


Mass


IR : liquid film


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