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化合物简介
Triethyl Methanetricarboxylate is used in the synthesis of novel inhibitors of Hsp90. It is also used in the preparation of novel dihydroquinoline-3-carboxylic acids that function as HIV-1 integrase inhibitors.
基本信息
CAS:6279-86-3
中文别名:三羧酸甲烷三乙酯;甲烷三甲酸三乙酯;
英文别名:Methanetricarboxylic acid, triethyl ester;2-Ethoxycarbonyl-malonic acid diethyl ester;Diethyl 2-(ethoxycarbonyl)malonate;Carboxymalonic Acid Triethyl Ester;tricarbethoxymethane;Methanetricarboxylic acid,triethyl ester;Triethylmethanetricarboxylate;tri(ethoxycarbonyl)methane;
分子式:C10H16O6
分子量:232.23
精确质量:232.095
Psa:78.9
Logp:0.2919
中文别名:三羧酸甲烷三乙酯;甲烷三甲酸三乙酯;
英文别名:Methanetricarboxylic acid, triethyl ester;2-Ethoxycarbonyl-malonic acid diethyl ester;Diethyl 2-(ethoxycarbonyl)malonate;Carboxymalonic Acid Triethyl Ester;tricarbethoxymethane;Methanetricarboxylic acid,triethyl ester;Triethylmethanetricarboxylate;tri(ethoxycarbonyl)methane;
分子式:C10H16O6
分子量:232.23
精确质量:232.095
Psa:78.9
Logp:0.2919
编号系统
EINECS号:228-477-2
MDL号:MFCD00009150
MDL号:MFCD00009150
物化性质
外观与性状:在熔点后,透明无色固体
密度:1.095g/mLat 25°C(lit.)
沸点:253°C(lit.)
熔点:25-26°C(lit.)
闪点:>230°F
折射率:n20/D 1.424(lit.)
水溶解性:immiscible
稳定性:Stable under normal temperatures and pressures.
储存条件:Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
密度:1.095g/mLat 25°C(lit.)
沸点:253°C(lit.)
熔点:25-26°C(lit.)
闪点:>230°F
折射率:n20/D 1.424(lit.)
水溶解性:immiscible
稳定性:Stable under normal temperatures and pressures.
储存条件:Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
安全信息
安全说明:S23-S24/25
WGK Germany:3
海关编码:29171990
WGK Germany:3
海关编码:29171990
生产方法及用途
用途
用作盐酸罗沙替丁醋酸酯中间体 医药中间体。
用作盐酸罗沙替丁醋酸酯中间体 医药中间体。
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict

13C NMR : in CDCl3

1H NMR : 400 MHz in CDCl3

Mass spectrum (electron ionization)

Mass

IR : liquid film
