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  • BMS 564929

    4-[(7R,7aS)-7-hydroxy-1,3-dioxo-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrile

化合物简介

BMS-564,929 is an investigational selective androgen receptor modulator, which is being developed by Bristol-Myers Squibb for treatment of the symptoms of age-related decline in androgen levels in men (\"andropause\"). These symptoms may include depression, loss of muscle mass and strength, reduction in libido and osteoporosis. Treatment with exogenous testosterone is effective in counteracting these symptoms but is associated with a range of side effects, the most serious of which is enlargement of the prostate gland, which can lead to benign prostatic hypertrophy and even prostate cancer. This means there is a clinical need for selective androgen receptor modulators, which produce anabolic effects in some tissues such as muscle and bone, but without stimulating androgen receptors in the prostate.

基本信息

CAS:627530-84-1
中文别名
英文别名:2nw4;hydantoin,3;
分子式:C14H12ClN3O3
分子量:305.716
精确质量:305.057
Psa:84.64
Logp:1.42478

编号系统

UNII:9BLW27W4X7

物化性质

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

1H NMR : Predict


13C NMR : Predict


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