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化合物简介

Piperacillin is a broad-spectrum β-lactam antibiotic of the ureidopenicillin class. The chemical structure of piperacillin and other ureidopenicillins incorporates a polar side chain that enhances penetration into Gram-(-) bacteria and reduces susceptibility to cleavage by Gram-(-) beta lactamase enzymes. These properties confer activity against the important hospital pathogen Pseudomonas aeruginosa. Thus piperacillin is sometimes referred to as an \"anti-pseudomonal penicillin\".

基本信息

CAS:61477-96-1
中文别名:(2S,5R,6R)-3,3-二甲基-6-[(4-乙基-2,3-二氧代-1-哌嗪甲酰氨基)苯乙酰氨基]-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-甲酸;氧哌嗪青霉素;
英文别名:PIPERACILLIN NA;PIPC;Piperacillin anhydrous;PIPERACILLIN SODIUM;PIPERAILLIN;Pipracil;Pipercillin;
分子式:C23H27N5O7S
分子量:517.555
精确质量:517.163
Psa:181.73
Logp:0.3552

编号系统

UNII:9I628532GX

物化性质

外观与性状:白色结晶粉末
密度:1.51 g/cm3
熔点:139-140ºC
储存条件:Hygroscopic, -20ºC Freezer, Under Inert Atmosphere

安全信息

海关编码:2941101900

生产方法及用途

用途
敏感菌所致的感染。

合成路线

上游原料

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图谱

13C NMR : Predict


1H NMR : Predict


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