URB602 ([1,1'-biphenyl]-3-yl-carbamic acid, cyclohexyl ester) is a compound that has been found to inhibit hydrolysis of monoacyl glycerol compounds, such as 2-arachidonoylglycerol (2-AG) and 2-oleoylglycerol (2-OG). It was first described in 2003. A study performed in 2005 found that the compound had specificity for metabolizing 2-AG over anandamide (another cannabinoid ligand) in rat brain presumably by inhibiting the enzyme monoacylglycerol lipase (MAGL), which is the primary metabolic enzyme of 2-AG. However, subsequent studies have shown that URB602 lacks specificity for MAGL inhibition in vitro.

CAS：565460-15-3
中文别名：[1,1-联苯]-3-氨基甲酸环己酯;
英文别名：N-Biphenyl-3-ylcarbamic acid,cyclohexyl ester;Monoacylglycerol Lipase Inhibitor,URB602;Biphenyl-3-yl Carbamic Acid,Cyclohexyl Ester;cyclohexyl ester;URB602;cyclohexyl biphenyl-3-ylcarbamate;
分子式：C19H21NO2
分子量：295.376
精确质量：295.157
Psa：38.33
Logp：5.3078

MDL号：MFCD08457914

外观与性状：灰白色固体
密度：1.149g/cm3
沸点：416.611ºC at 760 mmHg
熔点：122-123ºC
闪点：205.759ºC
折射率：1.595

海关编码：2924299090