8-Oxoguanine (8-hydroxyguanine, 8-oxo-Gua, or OH8Gua) is one of the most common DNA lesions resulting from reactive oxygen species and can result in a mismatched pairing with adenine resulting in G to T and C to A substitutions in the genome. In humans, it is primarily repaired by DNA glycosylase OGG1. It can be caused by ionizing radiation, in connection with oxidative metabolism.

CAS：5614-64-2
中文别名：8-羟基鸟嘌呤盐酸盐;
英文别名：8-OH-GUA;7,8-DIHYDRO-8-OXOGUANINE;2-AMINO-6,8-DIHYDROXYPURINE;8-Hydroxy-guanin;8-Oxo-7,8-dihydroguanine;8-OXOGUANINE;2-amino-7,9-dihydro-1H-purine-6,8-dione;2-AMINO-6,8-PURINEDIOL;1H-Purine-6,8-dione, 2-amino-7,9-dihydro-;8-Oxodihydroguanine;2-aminopurine-6,8-diol;8-HYDROXYGUANINE;8-OXOG;
分子式：C5H5N5O2
分子量：167.125
精确质量：167.044
Psa：120.94
Logp：-0.0725

MDL号：MFCD00005564

密度：2.49g/cm3
沸点：327.7ºC at 760 mmHg
熔点：>400ºC dec.
闪点：152ºC
折射率：2.156

安全说明：S24/25
海关编码：2933990090