Salsalate is a medication that belongs to the salicylate and non-steroidal anti-inflammatory drug (NSAID) classes. Relative to other NSAIDs, salsalate has a weak inhibitory effect on the cyclooxygenase enzyme and decreases the production of several proinflammatory chemical signals such as interleukin-6, TNF-alpha, and C-reactive protein. The mechanism through which salsalate is thought to reduce the production of these inflammatory chemical signals is through the inhibition of IκB kinase resulting in decreased action of NF-κB genes. This mechanism is thought to be responsible for salsalate's insulin-sensitizing and blood sugar lowering properties. Salsalate is the generic name of a prescription drug marketed under the brandnames Mono-Gesic, Salflex, Disalcid, and Salsitab. Other generic and brand name formulations may be available.

CAS：552-94-3
中文别名：水杨酸-2-羧基苯酯;水杨酸2-羧基苯酯;甲磺酸依普罗沙坦;水杨基水杨酸;2-羟基苯甲酸-2-羧基苯基酯;阿司匹林杂质E;
英文别名：Benzoic acid, 2-hydroxy-, 2-carboxyphenyl ester;2-salicyloyloxy-benzoic acid;2-(2-hydroxybenzoyl)oxybenzoic acid;Salicylsalicylic acid;Saloxium;Disalcid;Diacesal;Disalicylic acid;Sasapyrine;Diplosal;Salicyl salicylate;carboxyphenyl salicylate;Disalyl;Salsalate;sasapyrine;Sasapyrinum;
分子式：C14H10O5
分子量：258.226
精确质量：258.053
Psa：83.83
Logp：2.3096

UNII：V9MO595C9I

外观与性状：晶体
密度：1.404g/cm3
沸点：482.9ºC at 760 mmHg
熔点：139-151 °C
闪点：188ºC
水溶解性：水解
稳定性：Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件：Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

RTECS号：DH2080000
安全说明：37/39-26
危险类别码：R36/37/38
海关编码：2918230000
危险品标志：Xi

生产方法
暂无 非甾体抗炎药。
用途
非甾体抗炎药。