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  • 纳美芬

    (4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol

化合物简介

A structural analog of Naltrexone with opiate antagonist activity used in pharmaceutical treatment of alcoholism. Other pharmacological applications of this compound aim to reduce food cravings, drug abuse and pulmonary disease in affected individuals. Used as an opioid-induced tranquilizer on large animals in the veterinary industry. Narcotic antagonist.

基本信息

CAS:55096-26-9
中文别名:(5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol;(5Α)-17-(环丙基甲基)-4,5-环氧-6-亚甲基吗啡喃-3,14-二醇;
英文别名:6-desoxy-6-methylenenaltrexone;Nalmetreno;Revex;Arthene;Alcofene;Nalmefene;Nalmetrene;Nalmefenum;nalmefene;Nalmetrenum;Cervene;
分子式:C21H25NO3
分子量:339.428
精确质量:339.183
Psa:52.93
Logp:2.4504

编号系统

UNII:TOV02TDP9I

物化性质

熔点:188 - 190ºC
储存条件:2-8ºC

安全信息

安全说明:S26-S36
危险类别码:R36/37/38
WGK Germany:3
危险品标志:Xi

生产方法及用途

合成路线

上游原料

下游产品

图谱

Predict 1H proton NMR


13C NMR : Predict


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