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化合物简介
L-Norpseudoephedrine, or (−)-norpseudoephedrine, also referable to as (−)-threo-β-hydroxyamphetamine, is a psychostimulant drug of the amphetamine family. It is one of the four optical isomers of phenylpropanolamine, the other three being cathine ((+)-norpseudoephedrine), (−)-norephedrine, and (+)-norephedrine; as well as one of the two enantiomers of norpseudoephedrine (the other, of course, being cathine). Similarly to cathine, L-norpseudoephedrine acts as a releasing agent of norepinephrine (EC50 = 30 nM) and to a lesser extent of dopamine (EC50 = 294 nM). Due to the 10-fold difference in its potency for inducing the release of the two neurotransmitters however, L-norpseudoephedrine could be called a modestly selective or preferential norepinephrine releasing agent, similarly to related compounds like ephedrine and pseudoephedrine.
基本信息
CAS:53643-20-2
中文别名:
英文别名:(1R,2R)-1-phenyl-2-amino-1-propanol hydrochloride;(+)-(2R:3R)-threo-Norpseudoephedrinhydrochlorid;(-)-(1R,2R)-norpseudoephedrine hydrochloride;(1R,2R)-(+)-norpseudoephedrine hydrochloride;(1R,2R)-(-)-norpseudoephedrine hydrochloride;(1R,2R)-norpseudoephedrine hydrochloride;(IR,2R)-I-Norpseudoephedrine HCL;
分子式:C9H14ClNO
分子量:187.667
精确质量:187.076
Psa:46.25
Logp:2.5695
中文别名:
英文别名:(1R,2R)-1-phenyl-2-amino-1-propanol hydrochloride;(+)-(2R:3R)-threo-Norpseudoephedrinhydrochlorid;(-)-(1R,2R)-norpseudoephedrine hydrochloride;(1R,2R)-(+)-norpseudoephedrine hydrochloride;(1R,2R)-(-)-norpseudoephedrine hydrochloride;(1R,2R)-norpseudoephedrine hydrochloride;(IR,2R)-I-Norpseudoephedrine HCL;
分子式:C9H14ClNO
分子量:187.667
精确质量:187.076
Psa:46.25
Logp:2.5695
编号系统
物化性质
安全信息
生产方法及用途
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上游原料
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图谱
Raman : 4880 A,200 M,powder

Mass

IR : nujol mull

IR : KBr disc
